Childn 8 mg/kg as single dose or in 2 divided doses every 12 hr. Typhoid fever 15-20 mg/kg once daily or divided into 2 doses every 12 hr for 7-14 days. Max: 400 mg/day. Granules for oral suspAdult & childn >12 yr 20 mL once daily or 10 mL every 12 hr. Childn 7-12 yr 10-15 mL once daily or 5-7.5 mL every 12 hr, 3-6 yr 5-10 mL once daily or 2.5-5 mL every 12 hr, 1-2 yr 2.5-5 mL once daily or 1.25-2.5 mL every 12 hr. Usual treatment duration: 7-14 days. Oral dropsChildn 1-2 yr 2.5-5 mL once daily or 1.25-2.5 mL every 12 hr, 6-11 mth 2.5-5 mL once daily or 1.25-2.5 mL every 12 hr. Usual treatment duration: 7-14 days.
Serious acute hypersensitivity reactions. Clostridium difficile-associated diarrhea & colitis. Fall in prothrombin activity. Overgrowth of non-susceptible organisms including fungi on long-term or repeated use. Patients w/ history of colitis; kidney or liver impairment or poor nutritional state; receiving a protracted course of antimicrobial therapy or previously stabilized on anticoagulant therapy. False +ve direct Coombs' test; ketones in the urine using nitroprusside test; & glucose in the urine using Clinitest, Benedict's soln or Fehling's soln. Pregnancy & lactation. Childn <6 mth.
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